(24) We prospectively evaluated the effect of P. niruri intake on 24 h urinary biochemical parameters in an attempt to assess its in vivo effect in calcium stone forming (CSF) patients. ANTIOXIDANT AND ANTICANDIDAL ACTIVITY STUDIES ON PHYLLANTHIN COMPOUND FROM PHYLLANTHUS NIRURI / ANUSHA JR* , REMYA R V, SASI PREMILA JM, ALBIN T FLEMING** / International Journal of Pharmacy and Pharmaceutical Sicences, Vol 6, Suppl 2: pp 323-326. "Effects of an aqueous extract from Phyllanthus niruri on calcium oxalate crystallization in vitro." Urol. L. on Platelet Aggregation, PROTECTIVE The effect could be through its uricosuric action and partly through xanthine oxidase inhibition. Study of aqueous leaf extract was done in female Sprague-Dawley rats to illicit evidence of toxicity. (which may be Phyllanthus urinaria L.), an Asian species, instead of Phyllanthus niruri L. which appears to be from the Americas. • Hypoglycemic Effect: Treatment with P. niruri showed remarkable and significant decrease in blood glucose (p<0.05) compared with control NIDDM patients. The antihyperuricemic effect of the lignans was attributed to their uricosuric action. Phyllanthin showed the highest dose-dependent antihyperuricemic effect. Finely grind the Phyllanthus niruri and apply it to scabies to cure. (31) PMID: 16896689, Urol Res. 595-601 PHYTOCHEMICAL, PHARMACOLOGICAL AND PHARMACOKINETIC STUDIES OF PHYLLANTHUS NIRURI LINN. - Medicinal properties of Phyllanthus urinaria are the same as those of Phyllanthus niruri. (22) Results suggest P. niruri may have toxic effects at high doses and should be ingested with precautions. However, there is no scientific confirmation of the effects of use during pregnancy.Evaluating the effect of Phyllanthus niruri aqueous extract on the maternal toxicity, reproductive outcomes and . • Protective Against Aflatoxin Toxicity / ROLE OF PHYLLANTHUS NIRURI AGAINST NIMESULIDE INDUCED HEPATIC DAMAGE, Phyllanthus and gallstones. The main stem quite often branches at the base, producing many leafy branches in a clump. Histological studies of the effects of oral administration of aqueous extract of Phyllanthus amarus commonly used in ethno medical practice in Africa for the management of various ailments such as kidney stones, dysentery, jaundice, diarrhoea and urogenital diseases on the kidney of adult Wistar rats were carefully studied. HIV-1 Reverse Transcriptase Inhibitor from Phyllanthus niruri / Takahiro Ogata, Hirotaka Higuchi, Shunjni Mochida, Hideki Matsumoto, Akihisa Kato, Tohru Endo, Akira Kaji, Hideko Kaji / AIDS Research and Human Retroviruses, Vol 8, No 11 (1992) / https://doi.org/10.1089/aid.1992.8.1937, Hypoglycemic Potency of Selected Medicinal Plants in Nigeria, BMC Complementary and Alternative MedicineBMC series –, Chanca • Antioxidant / Hepatoprotective / Leaves and Fruits: Methanolic and aqueous extracts of fruits and leaves of P. niruri showed inhibition of lipid peroxidation (LPO), scavenging of DPPH radical and inhibition of reactive oxygen species (ROS) in vitro. Phyllanthus niruri has been widely used for liver diseases in traditional medicine. (14) (25) The extract also inhibits woodchuck hepatitis virus (WHV) DNA polymerase and binds to the surface antigen of WHV in vitro. nirtetralin and phyltetralin. Study evaluated the possible ameliorative effects of P. niruri on aflatoxins induced serological and biochemical changes in liver of rats. - Studies have showed anti-hepatotoxic, antilithic, anti-hypertensive, anti-HIV and anti-hepatitis B properties. Chanca piedra is used for kidney stones.It is also used for various disorders of the urinary tract, digestive tract, and liver . (38) • Antihypertensive • Immunomodulatory Flavonoid / Antioxidant: Study evaluated the radical scavenging and immunomodulatory properties of flavonoid isolated from P. niruri. - In Ayurvedic medicine, considered hepatoprotective, antiviral, antibacterial, analgesic, antispasmodic, and antidiabetic. Hypoglycaemic Effect of Medicinal Herb Phyllanthus (Niruri on Diabetic Patients of Type-II diabetes (NIDDM) / Idris, Ameira Ahmed Abubaker /Thesis / http://repository.sustech.edu/handle/123456789/4157 Calculi from Phyllanthus niruri-treated animals had a smoother, homogeneous surface compared to the spicule shape of calculi found in the untreated CaOx group. (51) Effects of an extract from P niruri on hepatitis B and woodchuck hepatitis viruses: In vitro and in vivo studies / P S Venkateswaran et al / Proc Natl Acad Sci, USA • Vol 84, pp 274-278, Jan 1987 Phyllanthus niruri is a perennial tropical shrub, which has been used for a wide range of diseases in South and south-east Asian traditional medicine, including but not limited to jaundice, diarrhoea, dyspepsia, genitourinary infections and renal stones. If you continue to use this site we will assume that you are happy with it. (44) - Used for baths in newborns. Vol 8, Issue 5 (2016) Keezhanelli.jpg 1,280 × 960; 518 KB. (4) • Antimetastatic and Apoptotic Effects: Study evaluated the antimetastatic potential of Phyllanthus niruri, P. urinaria, P. watsonii, and P. amarus on lung and breast cancer carcinoma cells. Study showed an inhibitory effect of P niruri extract on CaOx crystal growth and aggregation in human urine, suggesting an interference with the early stages of stone formation and presents an alternative form of treatment and / or prevention of urolithiasis. non Webster 1955; Mohanan, Fl. Take Phyllanthus niruri leaves, Karisilanganni, Basil, and cumin in equal quantity and grind it with fresh cow’s milk or coconut milk. Names of Phyllanthus Amarus in various languages of the world are also given. • Antihyperuricemic / Lignans / Phyllanthin: Detailed information related to Phyllanthus Niruri's uses, side-effects, reviews, questions . Species - P. niruri . physical & spiritual uses of odii aba and bomaguwakyi.please like, share & subscribe for more teachings. Distribution Faculty of Land & Food Resources. Results showed attenuation of blood glucose in all treatment groups with a significant decrease in Mean Arterial Blood Pressure. (2) Study suggests the effect of I. batatas and P. niruri on different hematologic parameters are due to folic acid and iron which are integral components in the production of RBC and hemoglobin. Barros, M. E., et al. It also combats kidney stones, hence the "stonebreaker" moniker. (45) How Phyllanthus Amarus is effective for various diseases is listed in repertory format. Piedra / Phyllanthus niruri, Phyto-Pharmacology 95 ($0.24/Count) $26.06 with Subscribe & Save discount. Protective Role of Phyllanthus niruri Extract against Thioacetamide-Induced Liver Cirrhosis in Rat Model / In indomethacin-, ethanol acid- and cold restraint stress-induced ulcer models, the extract significantly (p<0.05) inhibited development of induced ulcers. Traditional Uses of Bhumi amla Studies On The Effect Of Aqueous Extract Of Phyllanthus Niruri Leaf On Plasma Glucose Level And Some Hepatospecific Markers In Diabetic Wistar Rats / H U Nwanjo / The Internet Journal of Laboratory Medicine. (46) Study in male Swiss albino mice evaluated the anti-tumor activity of a hydro-alcoholic extract of whole plant on two stage process of skin carcinogenesis induced by topical application of DMBA. Results suggest the leaf extract protects the kidney from oxidative stress induced by diabetes. Study evaluated the protective role of PN extract against liver cirrhosis induced by TAA in rats. Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. niruri Inhibits Calcium Oxalate Endocytosis by Renal Tubular Cells: Phyllanthus Niruri is a widely used herbal home remedy known to possess analgesic (palliative), diuretic, gastric, febrifugal, antispasmodic and cell protective properties. (1) Studies have shown potential anti-diabetic action of PN. acetaminophen hepatotoxicity by increasing antioxidative defense. You never get tooth pain in your life. Keezhaarnelli Phyllanthus niruri 1.jpg 1,836 × 3,264; 2.46 MB. Bhoamali (Phyllanthus niruri).jpg 2,000 × 1,500; 641 KB. (36) Chanca piedra Phyllanthus niruri is a widespread tropical plant commonly found in coastal areas, known by the common names gale of the wind, stonebreaker or seed-under-leaf. - Plant has yielded various phytochemicals: flavonoids, alkaloids, terpenoids, lignans, polyphenols, tannins, coumarins, and saponins. (5) In Brazil, where the plant is known as Phyllanthus niruri is a plant used for years in Brazil to treat urinary calculi. Flowers are yellow and very numerous; monoecious with 1-3 staminate flowers and solitary pistillate flower borne axillary. In vitro study evaluated various extract for anti-urolithiatic effect with two standard drugs, Neeri and Cystone as control. (10) Phyto-Pharmacology Study found the NSPN to be safe and well tolerated in acute tonsillopharyngitis patients, with significant benefits as compared to placebo. The whole plant is used to make medicine. Phyllanthus Niruri is used for Liver diseases, Hepatitis, Viral infections, Dysentery, Influenza, Vaginitis, Tumors, Diabetes, Diuresis, Jaundice and other conditions. (16) The whole plant juice has been used for medicinal purpose. In herbal medicine, it has long played a role in treating several conditions, including urinary tract stones, dysentery, ulcers and swelling. - Used as emmenagogue and febrifuge. Sci. The leaf extract exhibited in vitro antioxidant activity with IC50 lower than ascorbic acid. • Antifertility: • Antioxidant / Hepatoprotective / Kidney and Testes Effects: • Effects of HIV Replication: • Analgesic / Antipyretic: Study evaluated aqueous and ethanolic extracts of P. niruri for analgesic and antipyretic effect using the Tail Immersion Model and Brewer's Yeast Induced Pyrexia Model respectively. Phyllanthus niruri serves as the best medicine for Jaundice, ulcer, throat disease, stomach pain, high heat, eye disease, menstrual problems, low appetite, skin disease, incurable ulcers, sinus, and bleeding. 1/1 • HIV-1 Reverse Transcriptase Inhibitory: An aqueous extract of Phyllanthus niruri inhibited human immunodeficiency virus type-1 reverse transcriptase (HIV-1-RT). Study showed PN to possess hepatoprotective activity against nimesulide-induced The extracts showed better analgesic and antipyretic potential when compared to standard drugs. The botanical name of the Keezhanelli is Phyllanthus niruri. Depending on the age, the medicine quantity can be reduced and given to small children too. (47) Results suggest a potential role of P. niruri as immunomodulator adjuvant therapy for TB patients. - In Haiti, decoction of • Antimicrobial: isolated from PN, was found to have inhibitory effects on platelet The keezhanelli is a flowering plant used in herbal medicine, which grows about 50-70 cm height. (18) Gen info Chanca piedra is Spanish for "stone breaker," used by indigenous peoples of the Amazon as an effective remedy for the treatment of gallstones and kidney stones.. Botany Sampasampalukan is an erect, branching, slender, smooth herb growing 50 to 60 centimeters high. Sci (2015) 4(6): pp 507-513 Phyllanthus urinaria is the "(red) seed under leaf" in the West Indies. In more recent years, however, P. niruri has been shown in modern medicine to cure or treat multiple disorders. The Phyllanthus Amarus Plants, offered by the company, are demanded by various clients across the globe. Until about 1980, taxonomists placed a number of species, including this one, under Phyllanthus niruri L. Where the name Phyllanthus niruri has been applied in older literature to African or Asian specimens, usually Phyllanthus amarus is intended, but sometimes also Phyllanthus debilis, Phyllanthus fraternus, Phyllanthus maderaspatensis or Phyllanthus rotundifolius. Results support the traditional use of PN for treatment of diabetes and arterial hypertension, and suggests a potential beneficial effect in patients with co-existing diabetic hypertension. Plant yields phyllanthin, previously identified as pseudo-chiratan. - Milky juice applied to offensive sores. 1) Bhumi Amla is also known as "Phyllanthus niruri" is a tropical plant that grows 50-70 cm in height.This herb is known as "Bhumi Amla" because it's a small plant present in Bhumi (land) usually found in rainy season. The aqueous leaf extract prevented the increase in amount of lipid peroxidation (LPO) product, MDA, and diminution of SOD, CAT, and GPx activity levels in the kidney of diabetic rats. The hot water extract of whole plant on oral . Flowers are axillary and solitary, pale green In vivo Evaluation of Analgesic Activities of Phyllanthus niruri Leaf Methanol Extract in Experimental Animal Models / A. O. Sijuade / Journal of Advances in Medical and Pharmaceutical Sciences, 8(3): pp 1-8 (2016) Phyllanthus Niruri. in rats, Protective Role of Phyllanthus niruri Extract against Thioacetamide-Induced Liver Cirrhosis in Rat Model, EFFECT OF PHYLLANTHUS NIRURI ON ALCOHOL AND POLYUNSATURATED FATTY ACID INDUCED OXIDATIVE STRESS IN LIVER, Phytochemicals from Phyllanthus niruri Linn. of the Amazon as an effective remedy for the treatment of gallstones Latin name- Phyllanthus niruri Linn., Phyllanthus amarus Family- Euphorbiaceae Bhumyamalaki - Phyllanthus niruri is an important liver protecting Ayurvedic herb and an ingredient of Chyawanprash. In all my readings (scientific articles) of this particular species, I've not ready anything about this plant being toxic for consumption. treatment on liver, kidney and testes in CCl4 induced hepatotoxic rats / A P Manjrekar, V Jisha, P Bag, B Adhikary, M Pai, A hegde and M Nandini / Indian Journ of Experimental Biology, Vol 46, July 2008, pp 514-520. Bhumi Amla (Phyllanthus niruri) - Uses & Health Benefits What is Bhumi Amla? (32) LEAVES BY HOMOGENOUS PRECIPITATION AND TURBIDITORY METHOD. Evaluation of (anti)genotoxic activities of Phyllanthus niruri L. in rat bone marrow using the micronucleus test / Fernando Márlisson de Queiroz; Kayo Wanderson de Oliveira Matias; Mylena Mylana Freire da Cunha; Aline Schwarz* / Braz. / Leaves: Study evaluated a methanolic extract of leaves for anti-inflammatory and anti-ulcer activity. (56) • Anti-malarial: 2013 / http://dx.doi.org/10.1590/S1984-82502013000100015 - Bark used as purgative. (60) The plant extracts were shown to inhibit MCF-7 (breast carcinoma) and A549 (lung carcinoma) cells growth with IC50 values ranging from 50-180 µg/ml and 65-470 µg/ml for methanolic and aqueous extracts, respectively. A 250 µl/L concentration showed the highest rate of inhibition. Planet Ayurveda Phyllanthus Niruri बिना डॉक्टर के पर्चे द्वारा मिलने वाली आयुर्वेदिक दवा है, जो मुख्यतः लिवर रोग, यूरिन इन्फेक्शन के इलाज के लिए उपयोग किया जाता है। इसके . http://dx.doi.org/10.1155/2014/834815
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